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MYELOFIBROSIS (Myeloproliferative Syndrome)

The bone marrow is the spongy, fatty tissue inside your bones. Bone marrows produce stem cells that will mature to become red blood cells, white blood cells, and platelets. The red blood cell is responsible for carrying oxygen to all parts of the body, the white blood cells help you in protecting your body from disease-causing organisms and other invaders, while the platelets, they are responsible for blood coagulation which helps you stop bleeding if you have an opened wound. Any illnesses or abnormalities on the bone marrow will affect the production of these cells.
Myelofibrosis is a medical disorder that greatly affects the bone marrow. It is a chronic blood cancer that will form excessive scar tissues in the bone marrow. The disorder will disrupt the normal function of the bone marrow in which it could no longer produce normal blood cells. This cancer is a rare type of chronic leukemia and it belongs to a group of diseases called myeloproliferative disorders.

Some experts believed that myelofibrosis or MF can be caused by abnormal blood stem cells in the bone marrow. Abnormal stem cells produce mature cells that grow quickly, causing severe scarring or fibrosis and chronic inflammation. The result will lead to anemia, weakness, fatigue, and splenomegaly or the enlargement of the spleen. Since the bone marrow can no longer produce blood cells, the spleen will have to work overtime to supply the body’s demand. This will enlarge the spleen due to the excessive workload.
There is no specific cause of myelofibrosis. However, researchers have considered an inherited mutated gene could cause the condition.

Aside from the main signs of myelofibrosis, symptoms can include:

  • Bruising
  • Fatigue
  • Bone pain
  • Shortness of breath
  • Paleness
  • Recurrent infection

To learn more about Myelofibrosis and its characteristics, please visit:

If you think you are suffering from Myelofibrosis you should seek medical assistance. You may also be entitled to Social Security Disability Benefits. The SSA considered Myelofibrosis as a medical condition that would make you eligible for SSDI and SSI. Social Security Administration (SSA) maintains a “Listing of Medical Impairments” (known as the blue book) that automatically qualify you for Social Security Disability Insurance (SSDI) or Supplemental Security Income (SSI).