Call us at

Call us at


Bullous diseases are an autoimmune disorder that affects the skin which is characterized by the formation of large, fluid-filled blisters. The fluid in the blisters is water and proteins that leaks from injured tissues. Generally, blisters form in response to an injury; examples are burn and irritations that involves the topmost layer of skin. However, the blisters formed due to injuries stated earlier will heal quickly and usually would not leave a scar. But blisters formed from a systemic disease can start at the deeper layers of the skin and can cover a wide area of the skin. These types of blisters will heal very slowly and will likely leave a scar.

There are many diseases that can cause blistering, usually an end result or one of the symptoms. But there are three autoimmune disorders that are considered the most serious: bullous pemphigoid, dermatitis herpetiformis, and pemphigus vulgaris. The autoimmune disease occurs when the body’s protector from bacteria, virus and foreign particles, attacks the body’s own tissues and cells. The immune system produces antibodies to combat disease-causing microorganism. However, a certain condition, such as genetic mutation can cause the immune system to malfunction and in this situation, the immune system attacks the body’s skin.

Bullous Pemphigoid

Bullous pemphigoid is an autoimmune disease that affects the skin. It is a rare skin condition that would allow the formation of large blisters. This blister develops in the skin that often flexes such as areas in the armpits, upper thighs, and lower abdomen. Bullous pemphigoid usually affects people older than 60 years of age. The skin disease occurs when the thin layer of tissue below the outer layer of the skin is attacked by the immune system. Aside from the immune system, certain medications can cause its development.

Dermatitis Herpetiformis

Dermatitis herpetiformis or DH is a skin condition that is characterized by the formation of itchy and burning skin rash. The skin disorder typically develops in the elbows, knees, scalp, and buttocks. DH would develop into people who are gluten intolerant. What occurs is that when a gluten intolerant individual eats rye, barley or oats, the immune system would immediately attack the small intestine. The antibody produced by the immune system is called IgA or immunoglobulin A. When IgA attacks the gluten, the structures formed will enter the bloodstream. This residue or structures would clog small blood vessels, especially those located in the skin. The white blood, attracted to these clogs, would release a chemical called “complement” that causes an itchy, blistery rash.

Pemphigus Vulgaris

Pemphigus Vulgaris occurs when the immune system attacks specific proteins in the skin and the mucous membrane which results in bonds being broken in the skin cells. This action would form blisters. There is no specific cause for this disorder, however, aside from being an autoimmune disorder, some medications are believed to have caused the skin disorder development.

To learn more about Bullous Disorders, please visit:

If you think you are suffering from Bullous Disease you should seek medical assistance. You may also be entitled to Social Security Disability Benefits. The SSA considered Bullous Disease as a medical condition that would make you eligible for SSDI and SSI. Social Security Administration (SSA) maintains a “Listing of Medical Impairments” (known as the blue book) that automatically qualify you for Social Security Disability Insurance (SSDI) or Supplemental Security Income (SSI).